Research group

Bioactive polymer systems

The aim of the basic and applied research and experimental development of the research group Bioactive polymer systems is to study polymer materials, which are able to interact specifically with living cells or tissues. Explored materials involve not only bulk materials, modified polymer surfaces, but also the whole palette of nanoparticles and composites with various properties (magnetic, drug transport etc.) and various surface modifications.
In the area of polymer synthesis at CPS, attention is paid primarily to biodegradable polyesters, polyanhydrides and polyurethanes and particularly to copolymers of lactic acid, which have wide range of potential use(s), from medical to agricultural and recycling applications. Other polymers are studied from the point of view of their characterisation, modification and processing.

Head of the group: doc. Ing. Petr Humpolíček, Ph.D.


Implemented projects

15-08287Y - “Immobilization of specific bioactive natural substances in functionalized biodegradable polymer matrices”

TE02000006 - The project TACR of Competence centre “Centre for alternative environment friendly high effective polymer antimicrobial agents for industrial applications” in consortium of Tomas Bata University and 7 companies. TBU Project investigator: Vladimír Sedlařík Implementation period: 2014 – 2019.

TH02020836 - “Development of novel environmentally friendly packaging with added value for food applications”

FV10756 - “Development of polymer carriers in sub-micro and nano-forms” (2016-2020)

QJ1310254 - “Research into the use of whey as dairy industry waste product, the production of antimicrobial compounds for the modification of hydrophilic polymer systems with the use in cosmetic and medical applications” - 2013-2017

LO1504 - Centrum polymerních systémů plus – 2015-2020

7AMB16PL070 - “Novel processing techniques of biodegradable polymers for biomedical applications” (2016 – 2017)

QJ1310254 - “Research into the use of whey as dairy industry waste product, the production of antimicrobial compounds for the modification of hydrophilic polymer systems with the use in cosmetic and medical applications”, in cooperation with Tomas Bata University and 2 companies. TBU Project investigator: Vladimír Sedlařík Implementation period: 2013 – 2017.

Research outcomes

A novel multistep method for chondroitin sulphate immobilization and its interaction with fibroblast cells.

Citation data: Materials science & engineering. C, Materials for biological applications, ISSN: 1873-0191, Vol: 70, Issue: Pt 1, Page: 94-100

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Antimicrobial activity and cytotoxicity of cotton fabric coated with conducting polymers, polyaniline or polypyrrole, and with deposited silver nanoparticles

Citation data: Applied Surface Science, ISSN: 0169-4332, Vol: 396, Page: 169-176 Publication Year: 2017

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Versatile synthesis of comb-shaped poly(lactic acid) copolymers with poly(acrylic acid)-based backbones and carboxylic acid end groups

Citation data: Reactive and Functional Polymers, ISSN: 1381-5148, Vol: 111, Page: 79-87 Publication Year: 2017

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Formulation, Characterization and Properties of Hemp Seed Oil and Its Emulsions.

Citation data: Molecules (Basel, Switzerland), ISSN: 1420-3049, Vol: 22, Issue: 5, Page: 700 Publication Year: 2017

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Interaction of nanostructured TiO biointerfaces with stem cells and biofilm-forming bacteria

Materials science & engineering. C, Materials for biological applications, ISSN: 1873-0191, Vol: 77, Page: 500-507 Publication Year: 2017

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On the cytotoxicity of poly(4-aminodiphenylaniline) powders: Effect of acid dopant type and sample posttreatment

Citation data: International Journal of Polymeric Materials and Polymeric Biomaterials, ISSN: 0091-4037, Vol: 66, Issue: 3, Page: 132-138 Publication Year: 2017

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Variations of Polymer Porous Surface Structures via the Time-Sequenced Dosing of Mixed Solvents

Citation data: ACS applied materials & interfaces, ISSN: 1944-8252, Vol: 9, Issue: 7, Page: 6472-6481 Publication Year: 2017

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Chitosan-based nanocomplexes for simultaneous loading, burst reduction and controlled release of doxorubicin and 5-fluorouracil

International Journal of Biological Macromolecules. 2017, vol. 102, p. 613-624 ISSN: 0141-8130

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Cytotoxicity of poly(p-phenylenediamine)

Citation data: Chemical Papers, ISSN: 2585-7290, Vol: 71, Issue: 2, Page: 367-372 Publication Year: 2017

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Enhancement of temozolomide stability by loading in chitosan-carboxylated polylactide-based nanoparticles

Citation data: Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, ISSN: 1388-0764, Vol: 19, Issue: 2, Page: 71 Publication Year: 2017

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Cell-compatible conducting polyaniline films prepared in colloidal dispersion mode.

Citation data: Colloids and surfaces. B, Biointerfaces, ISSN: 1873-4367, Vol: 157, Page: 309-316 Publication Year: 2017

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Biological properties of printable polyaniline and polyaniline–silver colloidal dispersions stabilized by gelatin

Citation data: Synthetic Metals, ISSN: 0379-6779, Vol: 232, Page: 52-59 Publication Year: 2017

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Could Titanium Dioxide Nanotubes Represent a Viable Support System for Appropriate Cells in Vascular Implants?

Citation data: Advances in Biomembranes and Lipid Self-Assembly, ISSN: 2451-9634, Vol: 25, Page: 1-39 Publication Year: 2017

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Formation of bacterial and fungal biofilm on conducting polyaniline

Citation data: Chemical Papers, ISSN: 2585-7290, Vol: 71, Issue: 2, Page: 505-512 Publication Year: 2017

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Contacts

Head of the group: doc. Ing. Petr Humpolíček, Ph.D.

Senior researcher


prof. Ing. Vladimír Sedlařík, Ph.D.

+420 57 603 8013 A412
+420 734 262 658
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research

doc. Ing. Petr Humpolíček, Ph.D.

+420 57 603 8035 A319
+420 734 792 298
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Ing. Martina Pummerová, Ph.D.

+420 57 603 1740 A311
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doc. Ing. Věra Kašpárková, CSc.

+420 57 603 1232
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doc. Ing. Marián Lehocký, Ph.D.

+420 57 603 1215 215/U1
+420 608 616 048
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Ing. Petr Stloukal, Ph.D.

+420 57 603 1729 A217
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Antonio Di Martino, Ph.D.

+420 57 603 1740 A311
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Junior researcher


RNDr. Eva Domincová Bergerová, Ph.D.

+420 57 603 1739 A310
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Ing. Petra Briestenská, Ph.D.

+420 57 603 1744 A318
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Ing. Jana Sedlaříková, Ph.D.

+420 57 603 1235 230/U1
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Mgr. Jiří Pacherník, Ph.D.

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Ing. Anna Hurajová, Ph.D.

+420 57 603 1744 A318
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Ing. Zdenka Capáková, Ph.D.

+420 57 603 8047 A321
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Diana Harea, Ph.D.

+420 57 603 1739 A310
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Kadir Özaltin, M.Sc., Ph.D.

+420 57 603 1741 A313
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Technical (support staff)


Ing. Daniela Veselá

+420 57 603 8047 A321
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research

Ph.D. students


Ing. Kateřina Skopalová

+420 57 603 1749 A328
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Mgr. Petra Rejmontová

+420 57 603 1749 A328
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Ing. Nikola Mikušová

+420 57 603 1749 A328
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Ing. Pavlína Holčapková

+420 57 603 1749 A328
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Kateryna Filatova, MSc.

+420 57 603 1749 A328
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Contacts

Management
Project Team

+420 734 262 658
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