Research group

Biomaterials

Biomaterials combine advanced material properties with biocompatibility. The research group is therefore interested in preparing smart materials that can respond to external stimuli, such as electric fields, by combining synthetic polymers, biopolymers and other materials such as metals or ceramics. The prepared materials are then tested by the lab for biocompatibility by studying the interaction with eukaryotic and prokaryotic model systems. The instrumentation allows testing of a wide range of biological properties of materials, from basic parameters such as cytotoxicity through interaction at biological interfaces to the growth of scaffolds in bioreactors. Tumour or immortalized lines or stem cells are used as model systems. In addition to biomaterials, the group also tests cosmetics, e.g. for photo-toxicity or transdermal absorption.

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.


Implemented projects

TE02000006 - “Centre for alternative environment friendly high effective polymer antimicrobial agents for industrial applications” in consortium of Tomas Bata University and 7 companies, 2014 – 2019.

TH02020836 - “Development of novel environmentally friendly packaging with added value for food applications”, 2017-2020

GA19-16861S – „Interaction of stem cell biomaterials in simulated in vivo conditions“, 2019-2021

TH03020117 - "Conductive materials and their application for antistatic and dissipative treatment of the paper and polymeric products", 2018-2021

TG03010052 - Sub-project "Technology of recycled plastics utilization for building-decorative components", 2018-2019

TG03010052 - Sub-project "Development of biodegradable material with improved processing properties", 2018-2019

TJ01000329 - "Sensory-active polymer blends containing products of advanced extraction techniques of selected plants", 2018-2019

TJ01000330 - "Novel plastics stabilizers based on natural bioactive compounds", 2018-2019

FV10756 - “Development of polymer carriers in sub-micro and nano-forms”, 2016-2020

FV30048 - "New additives for multifunctional modification of polymeric surfaces", 2018-2021

GA17-05095S – "Biomimetic materials based on conducting polymers", 2017-2019

GA17-05318S - "Conjugated polymers based materials as luminescence chemosensors", 2017-2019

GA17-10813S - "Novel plasma polymers with tunable stability and permeability", 2017-2019

QK1910392– „Environmentally friendly soil conservation materials for the crop production intensification based on renewable resource“, 2019-2023

8X17021 - "Antibacterial polymeric nanocomposites on the base of carbon nanomaterials", 2017-2018

IGA/CPS/2018/001 – "Biological properties of polymers", 2018

IGA/CPS/2018/003 – "Functionalized polymer composites", 2018

Research outcomes

Enzyme-catalyzed polymerization process: A novel approach to the preparation of polyaniline colloidal dispersions with an immunomodulatory effect

CITATION DATA: Biomacromolecules, VOL: 23, ISS: 8, https://doi.org/10.1021/acs.biomac.2c00371, PUBLICATION YEAR: 2022

Furcellaran surface deposition and its potential in biomedical applications

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 13, https://doi.org/10.3390/ijms23137439, PUBLICATION YEAR: 2022

Substantial drop of plasticizer migration from polyvinyl chloride catheters using co-extruded thermoplastic polyurethane layers

CITATION DATA: Materials Today Communications, VOL: 32, https://doi.org/10.1016/j.mtcomm.2022.103895, PUBLICATION YEAR: 2022

Dicarboxylated hyaluronate: Synthesis of a new, highly functionalized and biocompatible derivative

CITATION DATA: Carbohydrate Polymers, VOL: 292, https://doi.org/10.1016/j.carbpol.2022.119661, PUBLICATION YEAR: 2022

New approach to prepare cytocompatible 3D scaffolds via the combination of sodium hyaluronate and colloidal particles of conductive polymers

CITATION DATA: Scientific Reports, VOL: 12, ISS: 1, https://doi.org/10.1038/s41598-022-11678-8, PUBLICATION YEAR: 2022

Novel Slippery Liquid-Infused Porous Surfaces (SLIPS) based on electrospun polydimethylsiloxane/polystyrene fibrous structures infused with natural blackseed oil

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 7, https://doi.org/10.3390/ijms23073682, PUBLICATION YEAR: 2022

The effect of surface substrate treatments on the bonding strength of aluminium inserts with glass-reinforced poly(phenylene) sulphide

CITATION DATA: Materials, VOL: 15, ISS: 5, https://doi.org/10.3390/ma15051929, PUBLICATION YEAR: 2022

Hierarchically structured surfaces prepared by phase separation: Tissue mimicking culture substrate

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 5, https://doi.org/10.3390/ijms23052541, PUBLICATION YEAR: 2022

Cross-linked gelatine by modified dextran as a potential bioink prepared by a simple and non-toxic process

CITATION DATA: Polymers, VOL: 14, ISS: 3, https://doi.org/10.3390/polym14030391, PUBLICATION YEAR: 2022

Comparison of dialdehyde polysaccharides as crosslinkers for hydrogels: The case of poly(vinyl alcohol)

CITATION DATA: Carbohydrate Polymers, VOL: 279, https://doi.org/10.1016/j.carbpol.2021.119022, PUBLICATION YEAR: 2022

Tuning the conductivity, morphology, and capacitance with enhanced antibacterial properties of polypyrrole by acriflavine hydrochloride

CITATION DATA: ACS Applied Polymer Materials, VOL: 3, ISS: 12, https://doi.org/10.1021/acsapm.1c00775, PUBLICATION YEAR: 2021

Surface modification of metallic inserts for enhancing adhesion at the metal–polymer interface

CITATION DATA: Polymers, VOL: 13, ISS: 22, https://doi.org/10.3390/polym13224015, PUBLICATION YEAR: 2021

Contacts

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.

Scientific team


prof. Ing. Petr Humpolíček, Ph.D.

+420 57 603 8035 A319
+420 734 792 298
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Ing. Kateřina Skopalová, Ph.D.

+420 57 603 1749 A328
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Ing. Lucie Urbánková, Ph.D

+420 57 603 1742 A326
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doc. Zdenka Capáková, Ph.D.

+420 57 603 8047 A321
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doc. Ing. Věra Kašpárková, CSc.

+420 57 603 1232
+420 57 603 1742 A326
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doc. Ing. Marián Lehocký, Ph.D.

+420 57 603 1215 215/U1
+420 608 616 048
+420 57 603 8035 A319
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Kadir Özaltin, M.Sc., Ph.D.

+420 57 603 1741 A313
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Ph.D. students


Ing. Eva Korábková

+420 57 603 8128 A307
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Ing. Simona Káčerová

+420 57 603 1749 A328
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Ing. Martina Martínková

+420 57 603 1749 A328
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Ing. Leona Mahelová

+420 57 603 8128 A307
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Ing. Eliška Daďová

+420 57 603 3145 A307
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Ing. Kristýna Valášková

+420 57 603 3145 A307
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Ing. Daniela Jasenská

+420 57 603 8128 A307
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Ing. Than Huong Truong

+420 57 603 8128 A307
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Mgr. Jan Vajďák

+420 57 603 1479 A328
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Contacts

Management


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