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Research group

Biomaterials

Biomaterials combine advanced material properties with biocompatibility. The research group is therefore interested in preparing smart materials that can respond to external stimuli, such as electric fields, by combining synthetic polymers, biopolymers and other materials such as metals or ceramics. The prepared materials are then tested by the lab for biocompatibility by studying the interaction with eukaryotic and prokaryotic model systems. The instrumentation allows testing of a wide range of biological properties of materials, from basic parameters such as cytotoxicity through interaction at biological interfaces to the growth of scaffolds in bioreactors. Tumour or immortalized lines or stem cells are used as model systems. In addition to biomaterials, the group also tests cosmetics, e.g. for photo-toxicity or transdermal absorption.

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.

Contacts - Research team

Development of research direction

RP/CPS/2024-28/001 - Composite Biopolymers, 2024-2028
Principal Researcher: Mgr. Jan Vícha, Ph.D.

The main aim of the project is research into composite biomaterials (CB), namely:
I) "on-demand" responsive CBs with potential in regeneration (in situ or de novo) and monitoring mainly of heart and nervous tissue,
II) immunomodulating CBs, with potential for topical application and wound healing,
III) CB for targeted drug delivery, with potential for anti-inflammatory applications.

Implemented projects

HORIZON-JU-IA - SurfToGreen, 2024-2029

NW24-03-00331 -Selectively modified betaglucans as immunoactivatory carriers of anticancer drugs for the treatment of colon cancer, 2024-2027

GA24-11534S - Conductive (bio)polymer composites with covalently anchored polypyrrole for biomedical applications - 2024-2026

Completed projects

GA23-07425S - Anisotropic and Electro-Conducting Biomaterials - 2023-2025

GA20-28732S - Colloidal systems for topical formulations. Pickering emulsions and polymer based colloids, 2020-2022

GA19-16861S – „Interaction of stem cell biomaterials in simulated in vivo conditions“, 2019-2021

GA17-05095S – "Biomimetic materials based on conducting polymers", 2017-2019

GA17-10813S - "Novel plasma polymers with tunable stability and permeability", 2017-2019

8X17021 - "Antibacterial polymeric nanocomposites on the base of carbon nanomaterials", 2017-2018

Research outcomes

Controlling the biodegradation of polyhydroxybutyrate (PHB) and polybutylene succinate (PBS) by different types of lignin

CITATION DATA: Journal of Polymer Research, VOL: 32, ISS: 11, https://doi.org/10.1007/s10965-025-04644-1, PUBLICATION YEAR: 2025
Open in TBU repository

Unveiling the spatial architecture of biodegradable polyester plastisphere in soil and its implications for organic matter composition

CITATION DATA: Soil Biology & Biochemistry, VOL: 214, https://doi.org/10.1016/j.soilbio.2025.110050, PUBLICATION YEAR: 2026
Open in TBU repository

Optimizing electrochemical deposition for biodegradable zinc-hydroxyapatite systems in bone repair

CITATION DATA: ACS Omega, VOL: 11, ISS: 1, https://doi.org/10.1021/acsomega.5c08241, PUBLICATION YEAR: 2026
Open in TBU repository

Tuning the biodegradation rate of poly(3-hydroxybutyrate) by incorporating acidified or oxidized biochar

CITATION DATA: International Journal of Biological Macromolecules, VOL: 330, ISS: 3, https://doi.org/10.1016/j.ijbiomac.2025.148088, PUBLICATION YEAR: 2025
Open in TBU repository

Comparison of plasma polymerized thin films deposited from 2-methyl-2-oxazoline and 2-ethyl-2-oxazoline: II analysis of deposition process

CITATION DATA: International Journal of Molecular Sciences, VOL: 26, ISS: 17, https://doi.org/10.3390/ijms26178641, PUBLICATION YEAR: 2025
Open in TBU repository

Plasma mediated immobilization of metformin on polyethylene: effects on drug release, antibacterial activity, and biocompatibility

CITATION DATA: Journal of Biomaterials Science, Polymer Edition, VOL: 37, ISS: 2, https://doi.org/10.1080/09205063.2025.2524261, PUBLICATION YEAR: 2026
Open in TBU repository

Freeze-dried pickering emulsions with curcumin: The role of stabilizers and cryoprotectants

CITATION DATA: ACS Omega, VOL: 10, ISS: 26, https://doi.org/10.1021/acsomega.4c09731, PUBLICATION YEAR: 2025
Open in TBU repository

Thermoresponsive hyaluronate-based nanogels for enhanced phenanthriplatin delivery in cisplatin-resistant ovarian cancer

CITATION DATA: Biomacromolecules, VOL: 26, ISS: 8, https://doi.org/10.1021/acs.biomac.5c00692, PUBLICATION YEAR: 2025
Open in TBU repository

Dialdehyde polysaccharides as templates for green synthesis of polypyrrole-based materials without oxidative polymerization

CITATION DATA: ACS Sustainable Chemistry and Engineering, VOL: 13, ISS: 22, https://doi.org/10.1021/acssuschemeng.5c02711, PUBLICATION YEAR: 2025
Open in TBU repository

Tailoring of the physicochemical and biological properties of polypyrrole colloids with the help of stabilizers

CITATION DATA: Colloids and Surfaces A: Physicochemical and Engineering Aspects, VOL: 727, https://doi.org/10.1016/j.colsurfa.2025.138124, PUBLICATION YEAR: 2025
Open in TBU repository

Activation of NdFeB magnetic material upon exposure to oxygen plasma

CITATION DATA: Applied Surface Science, VOL: 713, https://doi.org/10.1016/j.apsusc.2025.164339, PUBLICATION YEAR: 2025
Open in TBU repository

One-step fabrication of chitosan/dialdehyde cellulose/polypyrrole composite nanofibers with antibacterial, antioxidant, and immunomodulatory effects

CITATION DATA: International Journal of Biological Macromolecules, VOL: 308, ISS: Part 1, https://doi.org/10.1016/j.ijbiomac.2025.142105, PUBLICATION YEAR: 2025
Open in TBU repository

Contacts

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.

Scientific team
Ph.D. students
  • prof. Ing. Petr Humpolíček, Ph.D.
  • +420 57 603 8035
  • +420 734 792 298
  • A319
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  • research
  • doc. Ing. Věra Kašpárková, CSc.
  • +420 57 603 1232
  • +420 57 603 1742
  • A326
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  • research

  • doc. Ing. Zdenka Víchová, Ph.D.

  • +420 57 603 8047
  • A321

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  • research

  • Ing. Monika Muchová, Ph.D.

  • +420 57 603 8117

  • A209

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  • Ing. Lukáš Münster, Ph.D.

  • +420 57 603 1729

  • A217

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  • Kadir Özaltin, M.Sc., Ph.D.
  • +420 57 603 1741

  • A313

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  • research
  • RNDr. Mariana Romžová, Ph.D.
  • +420 57 603 8117

  • A209

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  • Ing. Lucie Urbánková, Ph.D.

  • +420 57 603 1215

  • 330/U11

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  • Ing. Kristýna Valášková, Ph.D.
  • +420 57 603 1741
  • A313
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  • Mgr. Ondřej Vašíček, Ph.D.

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  • Mgr. Jan Vícha, Ph.D.

  • +420 57 603 1729

  • A217

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  • Ing. Eliška Daďová
  • +420 57 603 3145
  • A307
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  • Ing. Vítek Hrbáček

  • +420 57 603 1721

  • A207

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  • Ing. Filip Latečka

  • +420 57 603 1721

  • A207

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  • Prasad Parvathy
  • +420 57 603 1749
  • A307
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  • Ing. Marie Schrammová

  • +420 57 603 8128

  • A307

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  • Ing. Adam Srnec
  • +420 57 603 8128
  • A307
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