Research group

Biomaterials

Biomaterials combine advanced material properties with biocompatibility. The research group is therefore interested in preparing smart materials that can respond to external stimuli, such as electric fields, by combining synthetic polymers, biopolymers and other materials such as metals or ceramics. The prepared materials are then tested by the lab for biocompatibility by studying the interaction with eukaryotic and prokaryotic model systems. The instrumentation allows testing of a wide range of biological properties of materials, from basic parameters such as cytotoxicity through interaction at biological interfaces to the growth of scaffolds in bioreactors. Tumour or immortalized lines or stem cells are used as model systems. In addition to biomaterials, the group also tests cosmetics, e.g. for photo-toxicity or transdermal absorption.

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.

Contacts - Research team

Development of research direction

RP/CPS/2024-28/001 - Composite Biopolymers, 2024-2028
Principal Researcher: Mgr. Jan Vícha, Ph.D.

The main aim of the project is research into composite biomaterials (CB), namely:
I) "on-demand" responsive CBs with potential in regeneration (in situ or de novo) and monitoring mainly of heart and nervous tissue,
II) immunomodulating CBs, with potential for topical application and wound healing,
III) CB for targeted drug delivery, with potential for anti-inflammatory applications.

Implemented projects

HORIZON-JU-IA - SurfToGreen, 2024-2029,

NW24-03-00331 -Selectively modified betaglucans as immunoactivatory carriers of anticancer drugs for the treatment of colon cancer, 2024-2027

GA24-11534S - Conductive (bio)polymer composites with covalently anchored polypyrrole for biomedical applications - 2024-2026

GA23-07425S Anisotropic and Electro-Conducting Biomaterials - 2023-2025

IGA/CPS/2024/007 - Designing Smart Biomaterials for Tissue Engineering

Completed projects

GA20-28732S - Colloidal systems for topical formulations. Pickering emulsions and polymer based colloids, 2020-2022

GA19-16861S – „Interaction of stem cell biomaterials in simulated in vivo conditions“, 2019-2021

GA17-05095S – "Biomimetic materials based on conducting polymers", 2017-2019

GA17-10813S - "Novel plasma polymers with tunable stability and permeability", 2017-2019

8X17021 - "Antibacterial polymeric nanocomposites on the base of carbon nanomaterials", 2017-2018

IGA/CPS/2018/001 – "Biological properties of polymers", 2018

IGA/CPS/2018/003 – "Functionalized polymer composites", 2018

Research outcomes

Engineering of inhalable nano-in-microparticles for co-delivery of small molecules and miRNAs

CITATION DATA: Nanoscale Research Letters, VOL: 18, ISS: 1, https://doi.org/10.1186/s11671-023-03781-0, PUBLICATION YEAR: 2023
Open in TBU repository

Biodiesel from rapeseed and sunflower oil: Effect of the transesterification conditions and oxidation stability

CITATION DATA: Energies, VOL: 16, ISS: 2, https://doi.org/10.3390/en16020657, PUBLICATION YEAR: 2023
Open in TBU repository

Antibacterial thin films deposited from propane-butane mixture in atmospheric pressure discharge

CITATION DATA: International Journal of Molecular Sciences, VOL: 24, ISS: 2, https://doi.org/10.3390/ijms24021706, PUBLICATION YEAR: 2023
Open in TBU repository

Biodegradable polyesters and low molecular weight polyethylene in soil: Interrelations of material properties, soil organic matter substances, and microbial community

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 24, https://doi.org/10.3390/ijms232415976, PUBLICATION YEAR: 2022
Open in TBU repository

Controlled release of vitamin U from microencapsulated brassica oleracea l. var. capitata extract for peptic ulcer treatment

CITATION DATA: Food and Bioprocess Technology, VOL: 16, ISS: 3, https://doi.org/10.1007/s11947-022-02965-3, PUBLICATION YEAR: 2023
Open in TBU repository

Selected simple natural antimicrobial terpenoids as additives to control biodegradation of polyhydroxy butyrate

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 22, https://doi.org/10.3390/ijms232214079, PUBLICATION YEAR: 2022
Open in TBU repository

Influence of metal oxide nanoparticles as antimicrobial additives embedded in waterborne coating binders based on self-crosslinking acrylic latex

CITATION DATA: Coatings, VOL: 12, ISS: 10, https://doi.org/10.3390/coatings12101445, PUBLICATION YEAR: 2022
Open in TBU repository

Powder injection molded ceramic scaffolds: The role of pores size and surface functionalization on the cytocompatibility

CITATION DATA: Materials and Design, VOL: 224, https://doi.org/10.1016/j.matdes.2022.111274, PUBLICATION YEAR: 2022
Open in TBU repository

Formulation of magneto-responsive hydrogels from dually cross-linked polysaccharides: Synthesis, tuning and evaluation of rheological properties

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 17, https://doi.org/10.3390/ijms23179633, PUBLICATION YEAR: 2022
Open in TBU repository

Effect of saccharides coating on antibacterial potential and drug loading and releasing capability of plasma treated polylactic acid films

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 15, https://doi.org/10.3390/ijms23158821, PUBLICATION YEAR: 2022
Open in TBU repository

Enzyme-catalyzed polymerization process: A novel approach to the preparation of polyaniline colloidal dispersions with an immunomodulatory effect

CITATION DATA: Biomacromolecules, VOL: 23, ISS: 8, https://doi.org/10.1021/acs.biomac.2c00371, PUBLICATION YEAR: 2022
Open in TBU repository

Furcellaran surface deposition and its potential in biomedical applications

CITATION DATA: International Journal of Molecular Sciences, VOL: 23, ISS: 13, https://doi.org/10.3390/ijms23137439, PUBLICATION YEAR: 2022
Open in TBU repository

Contacts

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.

Scientific team
Ph.D. students
  • prof. Ing. Petr Humpolíček, Ph.D.
  • +420 57 603 8035
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  • A319
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  • doc. Ing. Věra Kašpárková, CSc.
  • +420 57 603 1232
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  • doc. Ing. Zdenka Víchová, Ph.D.

  • +420 57 603 8047
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  • Ing. Martina Martínková, Ph.D.

  • +420 57 603 1741

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  • Ing. Monika Muchová, Ph.D.

  • +420 57 603 8117

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  • Ing. Lukáš Münster, Ph.D.

  • +420 57 603 1729

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  • Kadir Özaltin, M.Sc., Ph.D.
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  • Ing. Kateřina Skopalová, Ph.D.
  • +420 57 603 1727
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  • Ing. Lucie Urbánková, Ph.D.

  • +420 57 603 1215

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  • Mgr. Ondřej Vašíček, Ph.D.

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  • Mgr. Jan Vícha, Ph.D.

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  • Ing. Eliška Daďová
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  • Ing. Hana Doudová

  • +420 57 603 1737

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  • Ing. Vítek Hrbáček

  • +420 57 603 1721

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  • Ing. Filip Latečka

  • +420 57 603 1721

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  • Ing. Leona Mahelová
  • +420 57 603 8128
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  • Prasad Parvathy
  • +420 57 603 1749
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  • Ing. Adam Srnec
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  • Ing. Kristýna Valášková
  • +420 57 603 3145
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